BDBM50291501 2-(2-p-Tolyl-ethyl)-thiophene-3-sulfonic acid (4-bromo-3-methyl-isoxazol-5-yl)-amide::CHEMBL174086

SMILES Cc1noc(NS(=O)(=O)c2ccsc2CCc2ccc(C)cc2)c1Br

InChI Key InChIKey=YRPDIYSYXUCGAU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50291501   

TargetEndothelin-1 receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50291501(2-(2-p-Tolyl-ethyl)-thiophene-3-sulfonic acid (4-b...)
Affinity DataIC50: 106nMAssay Description:Tested for its activity in cloned human Endothelin A receptor by using I-ET-1 as radioligand in a competitive radioligand assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetEndothelin receptor type B(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50291501(2-(2-p-Tolyl-ethyl)-thiophene-3-sulfonic acid (4-b...)
Affinity DataIC50: 1.17E+4nMAssay Description:Inhibition of human Endothelin B receptor using I-ET-1 as radioligand in a competitive radioligand assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article