BDBM50291492 2-(2-Benzo[1,3]dioxol-5-yl-vinyl)-thiophene-3-sulfonic acid (4-bromo-3-methyl-isoxazol-5-yl)-amide::CHEMBL367763

SMILES Cc1noc(NS(=O)(=O)c2ccsc2\C=C\c2ccc3OCOc3c2)c1Br

InChI Key InChIKey=JYOXXRCVFNUFLQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50291492   

TargetEndothelin receptor type B(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50291492(2-(2-Benzo[1,3]dioxol-5-yl-vinyl)-thiophene-3-sulf...)
Affinity DataIC50: 5.25E+3nMAssay Description:Inhibition of human Endothelin B receptor using I-ET-1 as radioligand in a competitive radioligand assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetEndothelin-1 receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50291492(2-(2-Benzo[1,3]dioxol-5-yl-vinyl)-thiophene-3-sulf...)
Affinity DataIC50: 141nMAssay Description:Tested for its activity in cloned human Endothelin A receptor by using I-ET-1 as radioligand in a competitive radioligand assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article