BDBM50291484 3-[2-(6-Hydroxymethyl-benzo[1,3]dioxol-5-yl)-vinyl]-thiophene-2-sulfonic acid (4-bromo-3-methyl-isoxazol-5-yl)-amide::CHEMBL366680

SMILES Cc1noc(NS(=O)(=O)c2sccc2\C=C\c2cc3OCOc3cc2CO)c1Br

InChI Key InChIKey=MEXKFSLYKSJPDY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50291484   

TargetEndothelin-1 receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50291484(3-[2-(6-Hydroxymethyl-benzo[1,3]dioxol-5-yl)-vinyl...)
Affinity DataIC50: 79nMAssay Description:Tested for its activity in cloned human Endothelin A receptor by using I-ET-1 as radioligand in a competitive radioligand assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetEndothelin receptor type B(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50291484(3-[2-(6-Hydroxymethyl-benzo[1,3]dioxol-5-yl)-vinyl...)
Affinity DataIC50: 3.24E+3nMAssay Description:Inhibition of human Endothelin B receptor using I-ET-1 as radioligand in a competitive radioligand assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article