BDBM50291445 (S)-2-(2-Mercapto-acetylamino)-4-methyl-pentanoic acid [(S)-2-(1H-indol-3-yl)-1-methylcarbamoyl-ethyl]-amide::CHEMBL426028

SMILES CNC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](CC(C)C)NC(=O)CS

InChI Key InChIKey=QNARFGGMEFFQAS-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50291445   

TargetMatrix metalloproteinase-9(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50291445((S)-2-(2-Mercapto-acetylamino)-4-methyl-pentanoic ...)
Affinity DataIC50: 30nMAssay Description:Compound was tested for its inhibitory activity against Matrix metalloprotease-9 (MMP-9) in adjuvant arthritic rat model of rheumatoid arthritisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetMetalloproteinase inhibitor 3(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50291445((S)-2-(2-Mercapto-acetylamino)-4-methyl-pentanoic ...)
Affinity DataIC50: 430nMAssay Description:Compound was tested for its inhibitory activity against Matrix metalloprotease-3 (MMP-3) in adjuvant arthritic rat model of rheumatoid arthritisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetNeutrophil collagenase(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50291445((S)-2-(2-Mercapto-acetylamino)-4-methyl-pentanoic ...)
Affinity DataIC50: 80nMAssay Description:Compound was tested for its inhibitory activity against Matrix metalloprotease-8 (MMP-8) in adjuvant arthritic rat model of rheumatoid arthritisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article