BDBM50291151 (4R,5R)-1,3,4-Tribenzyl-5-hydroxy-tetrahydro-pyrimidin-2-one::CHEMBL36380

SMILES O[C@@H]1CN(Cc2ccccc2)C(=O)N(Cc2ccccc2)[C@@H]1Cc1ccccc1

InChI Key InChIKey=GPADBRIUIALHNW-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50291151   

TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
TBA

Curated by ChEMBL
LigandPNGBDBM50291151((4R,5R)-1,3,4-Tribenzyl-5-hydroxy-tetrahydro-pyrim...)
Affinity DataKi:  2.5nMAssay Description:Compound was tested for the inhibitory activity against HIV-proteaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
TBA

Curated by ChEMBL
LigandPNGBDBM50291151((4R,5R)-1,3,4-Tribenzyl-5-hydroxy-tetrahydro-pyrim...)
Affinity DataKi:  2.40E+3nMAssay Description:Inhibition of HIV protease was measured by assay of the cleavage of a fluorescent peptide substrate. The fluorescent product (2-aminobenzoyl-Ala-Thr-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2004
Entry Details Article
PubMed