BDBM50291091 4-(3-Chloro-phenylsulfanyl)-6,7-dimethoxy-quinazoline::CHEMBL135902

SMILES COc1cc2ncnc(Sc3cccc(Cl)c3)c2cc1OC

InChI Key InChIKey=DLSREUWBAOWMKZ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50291091   

TargetTyrosine-protein kinase Lck(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50291091(4-(3-Chloro-phenylsulfanyl)-6,7-dimethoxy-quinazol...)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of p56lck kinase autophosphorylation in Jurkat cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2012
Entry Details Article

TargetEpidermal growth factor receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50291091(4-(3-Chloro-phenylsulfanyl)-6,7-dimethoxy-quinazol...)
Affinity DataIC50: 10nMAssay Description:Inhibition of Epidermal growth factor receptor autophosphorylation, 0.05-0.10More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2012
Entry Details Article