BDBM50291080 4-(3-Chloro-phenoxy)-6,7-dimethoxy-quinazoline::CHEMBL135853

SMILES COc1cc2ncnc(Oc3cccc(Cl)c3)c2cc1OC

InChI Key InChIKey=XDUSWBSGDKRQAF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50291080   

TargetTyrosine-protein kinase Lck(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50291080(4-(3-Chloro-phenoxy)-6,7-dimethoxy-quinazoline | C...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of p56lck kinase autophosphorylation in Jurkat cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2012
Entry Details Article

TargetEpidermal growth factor receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50291080(4-(3-Chloro-phenoxy)-6,7-dimethoxy-quinazoline | C...)
Affinity DataIC50: 20nMAssay Description:Inhibition of Epidermal growth factor receptor autophosphorylation, 0.05-0.10More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2012
Entry Details Article