BDBM50291031 (2R,3R,4R,5S)-2-Hydroxymethyl-1-(3-trimethylsilanyl-propyl)-piperidine-3,4,5-triol::CHEMBL121283

SMILES C[Si](C)(C)CCCN1C[C@H](O)[C@@H](O)[C@H](O)[C@H]1CO

InChI Key InChIKey=LSSAZCXUMNMRSK-UHFFFAOYSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50291031   

TargetSucrase-isomaltase, intestinal(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50291031((2R,3R,4R,5S)-2-Hydroxymethyl-1-(3-trimethylsilany...)
Affinity DataKi:  8nMAssay Description:Tested in vitro for the inhibition constant against rat small intestinal sucraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetSucrase-isomaltase, intestinal(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50291031((2R,3R,4R,5S)-2-Hydroxymethyl-1-(3-trimethylsilany...)
Affinity DataKi:  8nMAssay Description:Tested in vitro for the inhibition constant against rat small intestinal sucraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetMaltase-glucoamylase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50291031((2R,3R,4R,5S)-2-Hydroxymethyl-1-(3-trimethylsilany...)
Affinity DataKi:  50nMAssay Description:In vitro inhibition constant against rat small intestinal glucoamylaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetSucrase-isomaltase, intestinal(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50291031((2R,3R,4R,5S)-2-Hydroxymethyl-1-(3-trimethylsilany...)
Affinity DataKi:  120nMAssay Description:Tested in vitro for the inhibition constant against rat small intestinal isomaltaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetLysosomal alpha-glucosidase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50291031((2R,3R,4R,5S)-2-Hydroxymethyl-1-(3-trimethylsilany...)
Affinity DataKi:  2.50E+3nMAssay Description:Tested in vitro for the inhibition constant against human lysosomal alpha-glucosidaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article