BDBM50291004 4-[2-(1-Carbamimidoyl-2-hydroxy-piperidin-3-ylcarbamoyl)-pyrrolidin-1-yl]-4-oxo-3-(2-propyl-pentanoylamino)-butyric acid methyl ester::CHEMBL112726

SMILES CCCC(CCC)C(=O)N[C@@H](CC(=O)OC)C(=O)N1CCCC1C(=O)N[C@H]1CCCN(C1O)C(N)=N

InChI Key InChIKey=JCYOSRSLFRMEPO-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50291004   

TargetPlasminogen(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50291004(4-[2-(1-Carbamimidoyl-2-hydroxy-piperidin-3-ylcarb...)
Affinity DataIC50: 315nMAssay Description:In vitro inhibitory concentration required to inhibit human serine protease enzyme plasmin by 50%More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetProthrombin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50291004(4-[2-(1-Carbamimidoyl-2-hydroxy-piperidin-3-ylcarb...)
Affinity DataIC50: 1.10nMAssay Description:In vitro inhibitory concentration required to inhibit human serine protease enzyme thrombin (FIIa) by 50%More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetSerine protease 1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50291004(4-[2-(1-Carbamimidoyl-2-hydroxy-piperidin-3-ylcarb...)
Affinity DataIC50: 1.40nMAssay Description:In vitro inhibitory concentration required to inhibit human serine protease enzyme human trypsin by 50%More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetCoagulation factor X(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50291004(4-[2-(1-Carbamimidoyl-2-hydroxy-piperidin-3-ylcarb...)
Affinity DataIC50: 290nMAssay Description:In vitro inhibitory concentration required to inhibit Coagulation factor X by 50%More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article