BDBM50290963 (R)-4-Methyl-2-[2-(naphthalen-2-ylsulfanyl)-ethyl]-pentanoic acid ((S)-1-formyl-3-methyl-butyl)-amide::CHEMBL439590

SMILES CC(C)C[C@H](NC(=O)[C@@H](CCSc1ccc2ccccc2c1)CC(C)C)C=O

InChI Key InChIKey=WUCMINQNTKBQNK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50290963   

TargetCalpain-1 catalytic subunit(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50290963((R)-4-Methyl-2-[2-(naphthalen-2-ylsulfanyl)-ethyl]...)
Affinity DataIC50: 75nMAssay Description:Inhibitory activity using recombinant human Calpain 1 with Suc-Leu-Tyr-MNA as substrate.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetCathepsin B(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50290963((R)-4-Methyl-2-[2-(naphthalen-2-ylsulfanyl)-ethyl]...)
Affinity DataIC50: 60nMAssay Description:Inhibitory activity using cysteine protease, Cathepsin B with Cbz-Phe-Arg-AMC as substrate.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article