BDBM50290953 CHEMBL96762::N-[2-Benzo[1,3]dioxol-5-yl-2-(5-ethyl-3-methyl-6-oxo-6H-pyridazin-1-yl)-acetyl]-4-isopropyl-benzenesulfonamide

SMILES CCc1cc(C)nn(C(C(=O)NS(=O)(=O)c2ccc(cc2)C(C)C)c2ccc3OCOc3c2)c1=O

InChI Key InChIKey=UKUGWTYVQFDJIP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50290953   

TargetEndothelin-1 receptor(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50290953(N-[2-Benzo[1,3]dioxol-5-yl-2-(5-ethyl-3-methyl-6-o...)
Affinity DataIC50: 32nMAssay Description:Inhibition of specific binding of [125I]ET1 (endothelin 1) to the endothelin A receptor of rat aorta membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetEndothelin receptor type B(Pig)
TBA

Curated by ChEMBL
LigandPNGBDBM50290953(N-[2-Benzo[1,3]dioxol-5-yl-2-(5-ethyl-3-methyl-6-o...)
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of specific binding of [125I]ET1 (endothelin 1) to endothelin B receptor of porcine kidney membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article