BDBM50290952 CHEMBL330424::N-[2-Benzo[1,3]dioxol-5-yl-2-(3-methyl-6-oxo-6H-pyridazin-1-yl)-acetyl]-4-isopropyl-benzenesulfonamide

SMILES CC(C)c1ccc(cc1)S(=O)(=O)NC(=O)C(c1ccc2OCOc2c1)n1nc(C)ccc1=O

InChI Key InChIKey=LUQZWCBOERIKEO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50290952   

TargetEndothelin receptor type B(Pig)
TBA

Curated by ChEMBL
LigandPNGBDBM50290952(N-[2-Benzo[1,3]dioxol-5-yl-2-(3-methyl-6-oxo-6H-py...)
Affinity DataIC50: 2.90E+3nMAssay Description:Inhibition of specific binding of [125I]ET1 (endothelin 1) to endothelin B receptor of porcine kidney membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetEndothelin-1 receptor(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50290952(N-[2-Benzo[1,3]dioxol-5-yl-2-(3-methyl-6-oxo-6H-py...)
Affinity DataIC50: 34nMAssay Description:Inhibition of specific binding of [125I]ET1 (endothelin 1) to the endothelin A receptor of rat aorta membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article