BDBM50290949 CHEMBL94918::N-[2-Benzo[1,3]dioxol-5-yl-2-(3,5-dimethyl-6-oxo-6H-pyridazin-1-yl)-acetyl]-4-isopropyl-benzenesulfonamide

SMILES CC(C)c1ccc(cc1)S(=O)(=O)NC(=O)C(c1ccc2OCOc2c1)n1nc(C)cc(C)c1=O

InChI Key InChIKey=ACOIUSQYQHOULG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50290949   

TargetEndothelin receptor type B(Pig)
TBA

Curated by ChEMBL
LigandPNGBDBM50290949(N-[2-Benzo[1,3]dioxol-5-yl-2-(3,5-dimethyl-6-oxo-6...)
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibition of specific binding of [125I]ET1 (endothelin 1) to endothelin B receptor of porcine kidney membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetEndothelin-1 receptor(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50290949(N-[2-Benzo[1,3]dioxol-5-yl-2-(3,5-dimethyl-6-oxo-6...)
Affinity DataIC50: 29nMAssay Description:Inhibition of specific binding of [125I]ET1 (endothelin 1) to the endothelin A receptor of rat aorta membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article