BDBM50290943 CHEMBL94732::N-{2-Benzo[1,3]dioxol-5-yl-2-[3-(2,4-dimethoxy-phenyl)-6-oxo-5,6-dihydro-4H-pyridazin-1-yl]-acetyl}-4-isopropyl-benzenesulfonamide

SMILES COc1ccc(C2=NN(C(C(=O)NS(=O)(=O)c3ccc(cc3)C(C)C)c3ccc4OCOc4c3)C(=O)CC2)c(OC)c1

InChI Key InChIKey=NJZSWZOVZHVGPU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50290943   

TargetEndothelin receptor type B(Pig)
TBA

Curated by ChEMBL
LigandPNGBDBM50290943(N-{2-Benzo[1,3]dioxol-5-yl-2-[3-(2,4-dimethoxy-phe...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of specific binding of [125I]ET1 (endothelin 1) to endothelin B receptor of porcine kidney membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetEndothelin-1 receptor(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50290943(N-{2-Benzo[1,3]dioxol-5-yl-2-[3-(2,4-dimethoxy-phe...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of specific binding of [125I]ET1 (endothelin 1) to the endothelin A receptor of rat aorta membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article