BDBM50290941 CHEMBL412865::N-[2-Benzo[1,3]dioxol-5-yl-2-(6-oxo-3-thiophen-2-yl-5,6-dihydro-4H-pyridazin-1-yl)-acetyl]-4-isopropyl-benzenesulfonamide

SMILES CC(C)c1ccc(cc1)S(=O)(=O)NC(=O)C(N1N=C(CCC1=O)c1cccs1)c1ccc2OCOc2c1

InChI Key InChIKey=PYNWAKKYPKVAEA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50290941   

TargetEndothelin-1 receptor(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50290941(N-[2-Benzo[1,3]dioxol-5-yl-2-(6-oxo-3-thiophen-2-y...)
Affinity DataIC50: 3.20E+3nMAssay Description:Inhibition of specific binding of [125I]ET1 (endothelin 1) to the endothelin A receptor of rat aorta membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetEndothelin receptor type B(Pig)
TBA

Curated by ChEMBL
LigandPNGBDBM50290941(N-[2-Benzo[1,3]dioxol-5-yl-2-(6-oxo-3-thiophen-2-y...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of specific binding of [125I]ET1 (endothelin 1) to endothelin B receptor of porcine kidney membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article