BDBM50290940 CHEMBL94929::N-[2-Benzo[1,3]dioxol-5-yl-2-(3,5-dimethyl-6-oxo-6H-pyridazin-1-yl)-acetyl]-4-tert-butyl-benzenesulfonamide

SMILES Cc1cc(C)c(=O)n(n1)C(C(=O)NS(=O)(=O)c1ccc(cc1)C(C)(C)C)c1ccc2OCOc2c1

InChI Key InChIKey=JBVQBIGPUYFMOR-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50290940   

TargetEndothelin receptor type B(Pig)
TBA

Curated by ChEMBL
LigandPNGBDBM50290940(N-[2-Benzo[1,3]dioxol-5-yl-2-(3,5-dimethyl-6-oxo-6...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of specific binding of [125I]ET1 (endothelin 1) to endothelin B receptor of porcine kidney membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetEndothelin-1 receptor(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50290940(N-[2-Benzo[1,3]dioxol-5-yl-2-(3,5-dimethyl-6-oxo-6...)
Affinity DataIC50: 18nMAssay Description:Inhibition of specific binding of [125I]ET1 (endothelin 1) to the endothelin A receptor of rat aorta membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetEndothelin-1 receptor(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50290940(N-[2-Benzo[1,3]dioxol-5-yl-2-(3,5-dimethyl-6-oxo-6...)
Affinity DataIC50: 20nMAssay Description:Inhibition of specific binding of [125I]ET1 (endothelin 1) to the endothelin A receptor of rat aorta membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetEndothelin-1 receptor(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50290940(N-[2-Benzo[1,3]dioxol-5-yl-2-(3,5-dimethyl-6-oxo-6...)
Affinity DataIC50: 18nMAssay Description:Inhibition of specific binding of [125I]ET1 (endothelin 1) to the endothelin A receptor of rat aorta membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetEndothelin receptor type B(Pig)
TBA

Curated by ChEMBL
LigandPNGBDBM50290940(N-[2-Benzo[1,3]dioxol-5-yl-2-(3,5-dimethyl-6-oxo-6...)
Affinity DataIC50: 550nMAssay Description:Inhibition of specific binding of [125I]ET1 (endothelin 1) to endothelin B receptor of porcine kidney membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetEndothelin receptor type B(Pig)
TBA

Curated by ChEMBL
LigandPNGBDBM50290940(N-[2-Benzo[1,3]dioxol-5-yl-2-(3,5-dimethyl-6-oxo-6...)
Affinity DataIC50: 550nMAssay Description:Inhibition of specific binding of [125I]ET1 (endothelin 1) to endothelin B receptor of porcine kidney membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article