BDBM50290663 (7aR,10aS)-8-Propyl-7,7a,8,9,10,10a-hexahydro-6H-1-oxa-8-aza-dicyclopenta[a,h]naphthalene::CHEMBL328107

SMILES CCCN1CC[C@@H]2[C@H]1CCc1ccc3ccoc3c21

InChI Key InChIKey=ASNREPVWGRJPSG-UHFFFAOYSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50290663   

Target5-hydroxytryptamine receptor 1A(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50290663((7aR,10aS)-8-Propyl-7,7a,8,9,10,10a-hexahydro-6H-1...)
Affinity DataKi:  3.90nMAssay Description:Tested in vitro for the inhibition of [3H]8-OH-DPAT binding to 5-hydroxytryptamine 1A receptor, expressed in cloned CHO cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetSerotonin 2 (5-HT2) receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50290663((7aR,10aS)-8-Propyl-7,7a,8,9,10,10a-hexahydro-6H-1...)
Affinity DataKi:  146nMAssay Description:Tested in vitro for the inhibition of [3H]ketanserin binding to 5-hydroxytryptamine 2 receptor, expressed in cloned CHO cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetD(2) dopamine receptor(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50290663((7aR,10aS)-8-Propyl-7,7a,8,9,10,10a-hexahydro-6H-1...)
Affinity DataKi:  150nMAssay Description:Tested in vitro for the inhibition of [3H]raclopride binding to Dopamine receptor D2 in rat striatumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetD(3) dopamine receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50290663((7aR,10aS)-8-Propyl-7,7a,8,9,10,10a-hexahydro-6H-1...)
Affinity DataKi:  323nMAssay Description:Tested in vitro for the inhibition of [3H]U-86170 binding to Dopamine receptor D3, expressed in cloned CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetD(4) dopamine receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50290663((7aR,10aS)-8-Propyl-7,7a,8,9,10,10a-hexahydro-6H-1...)
Affinity DataKi: >4.07E+3nMAssay Description:Tested in vitro for the inhibition of [3H]spiperone binding to Dopamine receptor D4, expressed in cloned CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article