BDBM50290633 4-(2,3-Dihydro-indol-1-yl)-6,7-dimethoxy-quinazoline::CHEMBL328277::CHEMBL545776

SMILES COc1cc2ncnc(N3CCc4ccccc34)c2cc1OC

InChI Key InChIKey=HILIXBSGQQWNDX-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50290633   

LigandPNGBDBM50290633(CHEMBL328277 | CHEMBL545776 | 4-(2,3-Dihydro-indol...)
Affinity DataIC50: 5.00E+3nMAssay Description:Antagonism towards Colony stimulating factor 1 receptor (CSF-1R)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetEpidermal growth factor receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50290633(CHEMBL328277 | CHEMBL545776 | 4-(2,3-Dihydro-indol...)
Affinity DataIC50: 3.00E+3nMAssay Description:Antagonism towards Epidermal growth factor receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetEpidermal growth factor receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50290633(CHEMBL328277 | CHEMBL545776 | 4-(2,3-Dihydro-indol...)
Affinity DataIC50: 820nMAssay Description:Tested for inhibition of Epidermal growth factor receptor from A431 vulval squamous carcinoma cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetEpidermal growth factor receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50290633(CHEMBL328277 | CHEMBL545776 | 4-(2,3-Dihydro-indol...)
Affinity DataIC50: 4.10E+3nMAssay Description:Inhibition of EGF-stimulated proliferation of KB cells in cultureMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article