BDBM50290521 CHEMBL89076::Quinoline-2-carboxylic acid [(R)-1-((S)-1-{(2R,3S)-3-[2-(ethyl-isopropyl-sulfamoyl)-ethyl]-oxiranyl}-2-phenyl-ethylcarbamoyl)-2-methanesulfonyl-2-methyl-propyl]-amide

SMILES CCN(C(C)C)S(=O)(=O)CC[C@@H]1O[C@@H]1[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)c1ccc2ccccc2n1)C(C)(C)S(C)(=O)=O

InChI Key InChIKey=FCKCZIINZXEXBX-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50290521   

TargetCathepsin D(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50290521(Quinoline-2-carboxylic acid [(R)-1-((S)-1-{(2R,3S)...)
Affinity DataIC50: 8.20E+3nMAssay Description:Inhibition against human cathepsin D was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
TBA

Curated by ChEMBL
LigandPNGBDBM50290521(Quinoline-2-carboxylic acid [(R)-1-((S)-1-{(2R,3S)...)
Affinity DataKi:  7nMAssay Description:Compound was tested for its inhibitory activity against HIV-1 proteaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article