BDBM50290512 3-(2-{4-[Bis-(4-fluoro-phenyl)-methylene]-piperidin-1-yl}-ethyl)-6-{4-[4-(2-methoxy-phenyl)-piperazin-1-yl]-butyl}-3H-benzothiazol-2-one::CHEMBL314371

SMILES [#6]-[#8]-c1ccccc1-[#7]-1-[#6]-[#6]-[#7](-[#6]-[#6]-[#6]-[#6]-c2ccc3n(-[#6]-[#6]-[#7]-4-[#6]-[#6]\[#6](-[#6]-[#6]-4)=[#6](\c4ccc(F)cc4)-c4ccc(F)cc4)c(=O)sc3c2)-[#6]-[#6]-1

InChI Key InChIKey=KDJZEERBXSALFJ-UHFFFAOYSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50290512   

LigandPNGBDBM50290512(3-(2-{4-[Bis-(4-fluoro-phenyl)-methylene]-piperidi...)
Affinity DataKi:  5nMAssay Description:Binding affinity against Alpha-1 adrenergic receptor in rat cortex using [3H]prazosinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

Target5-hydroxytryptamine receptor 1A(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50290512(3-(2-{4-[Bis-(4-fluoro-phenyl)-methylene]-piperidi...)
Affinity DataKi:  5nMAssay Description:Binding affinity against 5-hydroxytryptamine 1A receptor of rat hippocampus using [3H]8-OH-DPATMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetD(2) dopamine receptor(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50290512(3-(2-{4-[Bis-(4-fluoro-phenyl)-methylene]-piperidi...)
Affinity DataKi:  5nMAssay Description:Binding affinity against D2 receptor in rat striatum using [3H]racloprideMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

Target5-hydroxytryptamine receptor 2A(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50290512(3-(2-{4-[Bis-(4-fluoro-phenyl)-methylene]-piperidi...)
Affinity DataKi:  7nMAssay Description:Binding affinity for 5-hydroxytryptamine 2A receptor in rat cortex using [3H]ketanserinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

Target5-hydroxytryptamine receptor 2C(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50290512(3-(2-{4-[Bis-(4-fluoro-phenyl)-methylene]-piperidi...)
Affinity DataKi:  110nMAssay Description:Binding affinity against 5-hydroxytryptamine 2C receptor in rat choroid plexus using [3H]N-methyl-mesulergineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article