BDBM50290472 CHEMBL4177038

SMILES CC(C)c1cc(C(=O)NCC(=O)Nc2ccc(F)c(Nc3ncc(Cl)c(Nc4ccccc4S(=O)(=O)C(C)C)n3)c2)c(O)cc1O

InChI Key InChIKey=DIHBQDURKIDMJF-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50290472   

TargetALK tyrosine kinase receptor(Human)
Shanghai Institute of Materia Medica (Simm)

Curated by ChEMBL
LigandPNGBDBM50290472(CHEMBL4177038)
Affinity DataIC50: 16nMAssay Description:Inhibition of recombinant ALK G1202R mutant (unknown origin) using poly (Glu,Tyr) 4:1 as substrate incubated for 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/29/2020
Entry Details Article
PubMed
TargetALK tyrosine kinase receptor(Human)
Shanghai Institute of Materia Medica (Simm)

Curated by ChEMBL
LigandPNGBDBM50290472(CHEMBL4177038)
Affinity DataIC50: 14nMAssay Description:Inhibition of recombinant ALK L1196M mutant (unknown origin) using poly (Glu,Tyr) 4:1 as substrate incubated for 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/29/2020
Entry Details Article
PubMed
TargetALK tyrosine kinase receptor(Human)
Shanghai Institute of Materia Medica (Simm)

Curated by ChEMBL
LigandPNGBDBM50290472(CHEMBL4177038)
Affinity DataIC50: 1nMAssay Description:Inhibition of recombinant ALK (unknown origin) using poly (Glu,Tyr) 4:1 as substrate incubated for 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/29/2020
Entry Details Article
PubMed