BDBM50290448 (R)-N*1*-((S)-2,2-Dimethyl-1-methylcarbamoyl-propyl)-N*4*-hydroxy-2-(14-hydroxy-tetradecyl)-succinamide::(R)-N1-((S)-3,3-dimethyl-1-(methylamino)-1-oxobutan-2-yl)-N4-hydroxy-2-(14-hydroxytetradecyl)succinamide::CHEMBL291994

SMILES CNC(=O)[C@@H](NC(=O)[C@H](CCCCCCCCCCCCCCO)CC(=O)NO)C(C)(C)C

InChI Key InChIKey=AMOCYMNNMVOHOG-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50290448   

Target72 kDa type IV collagenase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50290448((R)-N1-((S)-3,3-dimethyl-1-(methylamino)-1-oxobuta...)
Affinity DataIC50: 0.5nMAssay Description:Compound concentration for 50% inhibition of human recombinant gelatinase A (MMP-2).More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetInterstitial collagenase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50290448((R)-N1-((S)-3,3-dimethyl-1-(methylamino)-1-oxobuta...)
Affinity DataIC50: 300nMAssay Description:50% inhibition of human recombinant fibroblast collagenase (MMP-1, HFC)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetMatrilysin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50290448((R)-N1-((S)-3,3-dimethyl-1-(methylamino)-1-oxobuta...)
Affinity DataIC50: 500nMAssay Description:50% inhibition of human recombinant MatrilysinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetStromelysin-1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50290448((R)-N1-((S)-3,3-dimethyl-1-(methylamino)-1-oxobuta...)
Affinity DataIC50: 50nMAssay Description:Inhibition of human recombinant stromelysin (MMP-3, HFS)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetInterstitial collagenase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50290448((R)-N1-((S)-3,3-dimethyl-1-(methylamino)-1-oxobuta...)
Affinity DataIC50: 302nMAssay Description:Inhibition of human MMP1More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed