BDBM50290156 CHEMBL4162075

SMILES Nc1nc(N)nc(n1)-c1ccc(OCc2cccc(Cl)c2)cc1

InChI Key InChIKey=COIJIKNIEJYWAK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50290156   

TargetDihydrofolate reductase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
National University of Singapore

Curated by ChEMBL
LigandPNGBDBM50290156(CHEMBL4162075)
Affinity DataIC50: 5.62E+3nMAssay Description:Inhibition of Mycobacterium tuberculosis H37Rv DHFR assessed as reduction in consumption of NADPH using DHF as substrate incubated for 3 mins measure...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/28/2020
Entry Details Article
PubMed
TargetDihydrofolate reductase(Human)
National University of Singapore

Curated by ChEMBL
LigandPNGBDBM50290156(CHEMBL4162075)
Affinity DataIC50: 7.25E+4nMAssay Description:Inhibition of human DHFR assessed as reduction in consumption of NADPH using DHF as substrate incubated for 3 mins measured for 2 mins by spectrophot...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/28/2020
Entry Details Article
PubMed