BDBM50290074 CHEMBL558597::N-[(R)-1-(3-Amino-phenyl)-2-pyrrolidin-1-yl-ethyl]-2-(3,4-dichloro-phenyl)-N-methyl-acetamide; hydrochloride

SMILES CN([C@@H](CN1CCCC1)c1cccc(N)c1)C(=O)Cc1ccc(Cl)c(Cl)c1

InChI Key InChIKey=GZGGYQMNFMHDFI-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50290074   

TargetKappa-type opioid receptor(Guinea pig)
TBA

Curated by ChEMBL
LigandPNGBDBM50290074(N-[(R)-1-(3-Amino-phenyl)-2-pyrrolidin-1-yl-ethyl]...)
Affinity DataKi:  15nMAssay Description:Compound was evaluated for the inhibition of Opioid receptor kappa1 binding to guinea pig brain membranes, using 1 nM [3H]- U69,593 as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetMu-type opioid receptor(Guinea pig)
TBA

Curated by ChEMBL
LigandPNGBDBM50290074(N-[(R)-1-(3-Amino-phenyl)-2-pyrrolidin-1-yl-ethyl]...)
Affinity DataKi:  1.38E+3nMAssay Description:Compound was evaluated for the inhibition of Opioid receptor mu 1 binding to guinea pig brain membranes, using [3H]- DAMGO as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetDelta-type opioid receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50290074(N-[(R)-1-(3-Amino-phenyl)-2-pyrrolidin-1-yl-ethyl]...)
Affinity DataKi:  1.85E+3nMAssay Description:Compound was evaluated for the inhibition of Opioid receptor delta 1 binding to guinea pig brain membranes, using 0.2 nM [3H]naltrindole as radioliga...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article