BDBM50289967 CHEMBL4167860

SMILES COc1ccc(NC(=O)n2nc(cc2Cc2cc(Cl)ccc2OC)-c2sc(NC(=O)C(C)(C)C)nc2C)cc1

InChI Key InChIKey=DUWIJUNYFCPCQF-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50289967   

TargetCystic fibrosis transmembrane conductance regulator(Human)
University of Genoa

Curated by ChEMBL
LigandPNGBDBM50289967(CHEMBL4167860)
Affinity DataEC50:  1.00E+3nMAssay Description:Corrector activity at CFTR F508-del mutant (unknown origin) expressed in human CFBE41o cells harboring HS-YFP preincubated for 24 hrs followed by for...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/28/2020
Entry Details Article
PubMed