BDBM50289879 CHEMBL62205::[(S)-2-(1H-Indol-3-yl)-1-methyl-1-phenethylcarbamoyl-ethyl]-carbamic acid adamantan-2-yl ester

SMILES C[C@@](Cc1c[nH]c2ccccc12)(NC(=O)OC1C2CC3CC(C2)CC1C3)C(=O)NCCc1ccccc1

InChI Key

Data  2 KI  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50289879   

LigandPNGBDBM50289879([(S)-2-(1H-Indol-3-yl)-1-methyl-1-phenethylcarbamo...)
Affinity DataIC50: 48nMAssay Description:In vitro inhibition of [125I]- Bolton Hunter CCK-8 binding to Cholecystokinin type B receptor in the mouse cerebral cortex.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

TargetCholecystokinin receptor type A(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50289879([(S)-2-(1H-Indol-3-yl)-1-methyl-1-phenethylcarbamo...)
Affinity DataIC50: 377nMAssay Description:In vitro inhibition of [125I]- Bolton Hunter CCK-8 to Cholecystokinin type A receptor in the rat pancreas.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

LigandPNGBDBM50289879([(S)-2-(1H-Indol-3-yl)-1-methyl-1-phenethylcarbamo...)
Affinity DataIC50: 32nMAssay Description:Binding affinity towards Cholecystokinin type B receptor in mouse cortex membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2012
Entry Details Article
PubMed
TargetCholecystokinin receptor type A(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50289879([(S)-2-(1H-Indol-3-yl)-1-methyl-1-phenethylcarbamo...)
Affinity DataIC50: 650nMAssay Description:Compound was evaluated for the binding affinity towards rat pancreatic Cholecystokinin type A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2012
Entry Details Article
PubMed
LigandPNGBDBM50289879([(S)-2-(1H-Indol-3-yl)-1-methyl-1-phenethylcarbamo...)
Affinity DataIC50: 32nMAssay Description:Inhibition of binding of [125I]- Bolton-Hunter labeled CCK-8 to CCK-B receptor in the mouse cerebral cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetCholecystokinin receptor type A(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50289879([(S)-2-(1H-Indol-3-yl)-1-methyl-1-phenethylcarbamo...)
Affinity DataIC50: 650nMAssay Description:Inhibition of binding of [125I]- Bolton-Hunter labeled CCK-8 to CCK-A receptor in the rat pancreasMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

LigandPNGBDBM50289879([(S)-2-(1H-Indol-3-yl)-1-methyl-1-phenethylcarbamo...)
Affinity DataKi:  21nMAssay Description:Cholecystokinin type B receptor binding assay performed on homogenized cerebral cortex from male mouseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2019
Entry Details Article
PubMed
LigandPNGBDBM50289879([(S)-2-(1H-Indol-3-yl)-1-methyl-1-phenethylcarbamo...)
Affinity DataKi:  21.4nMAssay Description:Cholecystokinin type B receptor binding assay performed on homogenized cerebral cortex from male mouseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2019
Entry Details Article
PubMed