BDBM50289747 (S)-4-{(S)-2-Acetylamino-3-[4-(difluoro-phosphono-methyl)-phenyl]-propionylamino}-4-((S)-1-carbamoyl-3-cyclohexyl-propylcarbamoyl)-butyric acid::CHEMBL294692

SMILES CC(=O)N[C@@H](Cc1ccc(cc1)C(F)(F)P(O)(O)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCC1CCCCC1)C(N)=O

InChI Key InChIKey=LVVKADMQGHJKID-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50289747   

TargetTyrosine-protein kinase ABL1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50289747((S)-4-{(S)-2-Acetylamino-3-[4-(difluoro-phosphono-...)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of [35S]-labeled SH2-GST Abl binding to the phospho-PDGF receptor intracellular domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

LigandPNGBDBM50289747((S)-4-{(S)-2-Acetylamino-3-[4-(difluoro-phosphono-...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of [35S]-labeled SH2-GST Src binding to phospho-PDGF receptor intracellular domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

LigandPNGBDBM50289747((S)-4-{(S)-2-Acetylamino-3-[4-(difluoro-phosphono-...)
Affinity DataIC50: 4.90E+3nMAssay Description:Radioligand displacement assay for the binding of [125I]Glu-Pro-Gln-pTyr-Glu-Glu-Ile-Pro-Ile-Tyr-Leu to SRC SH2 domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetTyrosine-protein kinase ABL1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50289747((S)-4-{(S)-2-Acetylamino-3-[4-(difluoro-phosphono-...)
Affinity DataIC50: 1.20E+3nMAssay Description:Radioligand displacement assay for the binding of [125I]Glu-Pro-Gln-pTyr-Glu-Glu-Ile-Pro-Ile-Tyr-Leu to ABL SH2 domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article