BDBM50289746 CHEMBL298813::{[4-((S)-2-Acetylamino-2-{(S)-1-[(3-cyclohexyl-propyl)-methyl-carbamoyl]-propylcarbamoyl}-ethyl)-phenyl]-difluoro-methyl}-phosphonic acid

SMILES CC[C@H](NC(=O)[C@H](Cc1ccc(cc1)C(F)(F)P(O)(O)=O)NC(C)=O)C(=O)N(C)CCCC1CCCCC1

InChI Key InChIKey=QPFJPSMUHTYLAF-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50289746   

TargetTyrosine-protein kinase ABL1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50289746({[4-((S)-2-Acetylamino-2-{(S)-1-[(3-cyclohexyl-pro...)
Affinity DataIC50: 1.60E+3nMAssay Description:Radioligand displacement assay for the binding of [125I]Glu-Pro-Gln-pTyr-Glu-Glu-Ile-Pro-Ile-Tyr-Leu to ABL SH2 domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

LigandPNGBDBM50289746({[4-((S)-2-Acetylamino-2-{(S)-1-[(3-cyclohexyl-pro...)
Affinity DataIC50: 7.30E+3nMAssay Description:Inhibition of [35S]-labeled SH2-GST Src binding to phospho-PDGF receptor intracellular domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetTyrosine-protein kinase ABL1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50289746({[4-((S)-2-Acetylamino-2-{(S)-1-[(3-cyclohexyl-pro...)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of [35S]-labeled SH2-GST Abl binding to the phospho-PDGF receptor intracellular domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article