BDBM50289743 (S)-4-[(S)-2-Acetylamino-3-(4-phosphonooxy-phenyl)-propionylamino]-4-[(3-cyclohexyl-propyl)-methyl-carbamoyl]-butyric acid::CHEMBL13462

SMILES CN(CCCC1CCCCC1)C(=O)[C@H](CCC(O)=O)NC(=O)[C@H](Cc1ccc(OP(O)(O)=O)cc1)NC(C)=O

InChI Key InChIKey=DGXWTUANDHNVEV-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50289743   

LigandPNGBDBM50289743((S)-4-[(S)-2-Acetylamino-3-(4-phosphonooxy-phenyl)...)
Affinity DataIC50: 9.00E+3nMAssay Description:Inhibition of [35S]-labeled SH2-GST Src binding to phospho-PDGF receptor intracellular domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetTyrosine-protein kinase ABL1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50289743((S)-4-[(S)-2-Acetylamino-3-(4-phosphonooxy-phenyl)...)
Affinity DataIC50: 4.00E+3nMAssay Description:Radioligand displacement assay for the binding of [125I]Glu-Pro-Gln-pTyr-Glu-Glu-Ile-Pro-Ile-Tyr-Leu to ABL SH2 domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

LigandPNGBDBM50289743((S)-4-[(S)-2-Acetylamino-3-(4-phosphonooxy-phenyl)...)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of [125I]-labeled phosphopeptide binding to a Src protein tyrosine kinase SH2 domain.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetTyrosine-protein kinase ABL1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50289743((S)-4-[(S)-2-Acetylamino-3-(4-phosphonooxy-phenyl)...)
Affinity DataIC50: 1.60E+4nMAssay Description:Inhibition of [35S]-labeled SH2-GST Abl binding to the phospho-PDGF receptor intracellular domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

LigandPNGBDBM50289743((S)-4-[(S)-2-Acetylamino-3-(4-phosphonooxy-phenyl)...)
Affinity DataIC50: 800nMAssay Description:Radioligand displacement assay for the binding of [125I]Glu-Pro-Gln-pTyr-Glu-Glu-Ile-Pro-Ile-Tyr-Leu to SRC SH2 domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article