BDBM50289734 4-Benzo[1,3]dioxol-5-yl-1-(4-methoxy-benzyl)-2-oxo-1,2-dihydro-quinoline-3-carboxylic acid::CHEMBL293151

SMILES COc1ccc(Cn2c3ccccc3c(-c3ccc4OCOc4c3)c(C(O)=O)c2=O)cc1

InChI Key InChIKey=LGCDNSAAMULKRW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50289734   

TargetEndothelin receptor type B(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50289734(4-Benzo[1,3]dioxol-5-yl-1-(4-methoxy-benzyl)-2-oxo...)
Affinity DataIC50: 6.80E+3nMAssay Description:Inhibition of [125I]ET1 binding to porcine kidney inner medulla membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetEndothelin-1 receptor(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50289734(4-Benzo[1,3]dioxol-5-yl-1-(4-methoxy-benzyl)-2-oxo...)
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of [125I]ET1 binding to rat aorta membranes(ETA)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article