BDBM50289731 4-Benzo[1,3]dioxol-5-yl-5,6-dimethoxy-1-(2-methoxy-benzyl)-2-oxo-1,2-dihydro-quinoline-3-carboxylic acid::CHEMBL56348

SMILES COc1ccccc1Cn1c2ccc(OC)c(OC)c2c(-c2ccc3OCOc3c2)c(C(O)=O)c1=O

InChI Key InChIKey=QVSJREVIYZIYAS-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50289731   

TargetEndothelin-1 receptor(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50289731(4-Benzo[1,3]dioxol-5-yl-5,6-dimethoxy-1-(2-methoxy...)
Affinity DataIC50: 3.30E+3nMAssay Description:Inhibition of [125I]ET1 binding to rat aorta membranes(ETA)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetEndothelin receptor type B(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50289731(4-Benzo[1,3]dioxol-5-yl-5,6-dimethoxy-1-(2-methoxy...)
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of [125I]ET1 binding to porcine kidney inner medulla membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article