BDBM50289729 3-Benzo[1,3]dioxol-5-yl-5-ethoxy-1-(4-methoxy-benzyl)-1H-indole-2-carboxylic acid::CHEMBL55621

SMILES CCOc1ccc2n(Cc3ccc(OC)cc3)c(C(O)=O)c(-c3ccc4OCOc4c3)c2c1

InChI Key InChIKey=MJTVNBOCAMLCRC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50289729   

TargetEndothelin-1 receptor(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50289729(3-Benzo[1,3]dioxol-5-yl-5-ethoxy-1-(4-methoxy-benz...)
Affinity DataIC50: 1.30E+5nMAssay Description:Inhibition of [125I]ET1 binding to rat aorta membranes(ETA)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetEndothelin receptor type B(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50289729(3-Benzo[1,3]dioxol-5-yl-5-ethoxy-1-(4-methoxy-benz...)
Affinity DataIC50: 3.00E+5nMAssay Description:Inhibition of [125I]ET1 binding to porcine kidney inner medulla membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article