BDBM50289535 CHEMBL4176184

SMILES Clc1ccccc1Cc1cnc(NC(=O)C(c2ccccc2)c2ccccc2)s1

InChI Key InChIKey=PCCRSEBWEGGETI-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50289535   

TargetCystic fibrosis transmembrane conductance regulator(Human)
University of Genoa

Curated by ChEMBL
LigandPNGBDBM50289535(CHEMBL4176184)
Affinity DataEC50:  1.60E+4nMAssay Description:Corrector activity at CFTR F508-del mutant (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/28/2020
Entry Details Article
PubMed
TargetCystic fibrosis transmembrane conductance regulator(Human)
University of Genoa

Curated by ChEMBL
LigandPNGBDBM50289535(CHEMBL4176184)
Affinity DataEC50:  7.90E+3nMAssay Description:Potentiator activity at CFTR F508-del mutant (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/28/2020
Entry Details Article
PubMed