BDBM50289515 CHEMBL4172923

SMILES Fc1ccc(cc1)-c1csc(N\N=C\c2ccc(cc2)N2CCOCC2)n1

InChI Key InChIKey=IRGAJRYCAWQYPR-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50289515   

TargetAmine oxidase [flavin-containing] A(Human)
Anadolu University

Curated by ChEMBL
LigandPNGBDBM50289515(CHEMBL4172923)
Affinity DataIC50: 12nMAssay Description:Inhibition of human MAO-A using tyramine hydrochloride as substrate after 30 mins by Amplex Red reagent based horseradish peroxidase enzyme-coupled f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/27/2020
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
Anadolu University

Curated by ChEMBL
LigandPNGBDBM50289515(CHEMBL4172923)
Affinity DataIC50: 1.46E+4nMAssay Description:Inhibition of human MAO-B using tyramine hydrochloride as substrate after 30 mins by Amplex Red reagent based horseradish peroxidase enzyme-coupled f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/27/2020
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Human)
Anadolu University

Curated by ChEMBL
LigandPNGBDBM50289515(CHEMBL4172923)
Affinity DataKi:  6.60nMAssay Description:Reversible-competitive inhibition of human MAO-A using varying levels of tyramine as substrate after 30 mins by Lineweaver-Burk plotMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/27/2020
Entry Details Article
PubMed