BDBM50289513 CHEMBL4169527

SMILES Fc1ccc(-c2csc(N\N=C\c3ccc(cc3)N3CCOCC3)n2)c(F)c1

InChI Key InChIKey=KZVSBJZVZNNZGE-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50289513   

TargetAmine oxidase [flavin-containing] A(Human)
Anadolu University

Curated by ChEMBL
LigandPNGBDBM50289513(CHEMBL4169527)
Affinity DataIC50: 11nMAssay Description:Inhibition of human MAO-A using tyramine hydrochloride as substrate after 30 mins by Amplex Red reagent based horseradish peroxidase enzyme-coupled f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/27/2020
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
Anadolu University

Curated by ChEMBL
LigandPNGBDBM50289513(CHEMBL4169527)
Affinity DataIC50: 1.76E+4nMAssay Description:Inhibition of human MAO-B using tyramine hydrochloride as substrate after 30 mins by Amplex Red reagent based horseradish peroxidase enzyme-coupled f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/27/2020
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Human)
Anadolu University

Curated by ChEMBL
LigandPNGBDBM50289513(CHEMBL4169527)
Affinity DataKi:  4.40nMAssay Description:Reversible-competitive inhibition of human MAO-A using varying levels of tyramine as substrate after 30 mins by Lineweaver-Burk plotMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/27/2020
Entry Details Article
PubMed