BDBM50289425 3-[4-((R)-2-Amino-3-mercapto-propylamino)-phenoxy]-benzoic acid methyl ester::CHEMBL26149

SMILES COC(=O)c1cccc(Oc2ccc(NC[C@@H](N)CS)cc2)c1

InChI Key InChIKey=GDCNYLMHVAQGFE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50289425   

LigandPNGBDBM50289425(3-[4-((R)-2-Amino-3-mercapto-propylamino)-phenoxy]...)
Affinity DataIC50: 650nMAssay Description:Inhibition of the Farnesyltransferase catalyzed incorporation of [3H]FPP into recombinant Ha-Ras by 50% in bovine brain at a concentration of ca. 1 n...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

LigandPNGBDBM50289425(3-[4-((R)-2-Amino-3-mercapto-propylamino)-phenoxy]...)
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of Geranylgeranyl transferase type I, an enzyme that recognizes CaaX sequences containing leucine as the terminal residue.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article