BDBM50289372 (S)-1,1-Difluoro-3-isopropylamino-1-[4-(2-methoxy-ethyl)-phenoxy]-propan-2-ol::CHEMBL23929

SMILES COCCc1ccc(OC(F)(F)[C@@H](O)CNC(C)C)cc1

InChI Key InChIKey=UXOJFXXDDRFWJR-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50289372   

TargetBeta-1 adrenergic receptor(Guinea pig)
TBA

Curated by ChEMBL
LigandPNGBDBM50289372((S)-1,1-Difluoro-3-isopropylamino-1-[4-(2-methoxy-...)
Affinity DataIC50: 2.15E+3nMAssay Description:Tested for beta-2-adrenergic blocking effect by measuring the ability to inhibit the relaxing effect of epinephrine on the isolated tracheal muscle o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

LigandPNGBDBM50289372((S)-1,1-Difluoro-3-isopropylamino-1-[4-(2-methoxy-...)
Affinity DataIC50: 1.54E+3nMAssay Description:The compound was tested for its ability to inhibit (-)-[3H]dihydroalprenolol binding to beta-adrenergic receptor sites in rat cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetBeta-1 adrenergic receptor(Guinea pig)
TBA

Curated by ChEMBL
LigandPNGBDBM50289372((S)-1,1-Difluoro-3-isopropylamino-1-[4-(2-methoxy-...)
Affinity DataIC50: 1.35E+3nMAssay Description:Tested for beta-1-adrenergic blocking effect by measuring the ability to inhibit the positive inotropic effect of isoproterenol on the isolated right...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article