BDBM50289331 6-(3-Fluoro-phenyl)-5-(4-methanesulfonyl-phenyl)-2-trifluoromethyl-thiazolo[3,2-b][1,2,4]triazole::CHEMBL155927

SMILES CS(=O)(=O)c1ccc(cc1)-c1sc2nc(nn2c1-c1cccc(F)c1)C(F)(F)F

InChI Key InChIKey=URVFTJFHMOWIBI-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50289331   

TargetProstaglandin G/H synthase 1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50289331(6-(3-Fluoro-phenyl)-5-(4-methanesulfonyl-phenyl)-2...)
Affinity DataIC50: 8.50E+3nMAssay Description:Tested in vitro for the ability to inhibit Prostaglandin G/H synthase 1 in chinese hamster ovary (CHO) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetProstaglandin G/H synthase 2(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50289331(6-(3-Fluoro-phenyl)-5-(4-methanesulfonyl-phenyl)-2...)
Affinity DataIC50: 13nMAssay Description:In vivo ability to inhibit Prostaglandin G/H synthase 2 in human whole blood assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetProstaglandin G/H synthase 2(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50289331(6-(3-Fluoro-phenyl)-5-(4-methanesulfonyl-phenyl)-2...)
Affinity DataIC50: 1.29E+7nMAssay Description:Inhibition of COX2 (unknown origin) expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article