BDBM50289324 2-Isopropyl-5-(4-methanesulfonyl-phenyl)-6-phenyl-thiazolo[3,2-b][1,2,4]triazole::CHEMBL348115

SMILES CC(C)c1nc2sc(c(-c3ccccc3)n2n1)-c1ccc(cc1)S(C)(=O)=O

InChI Key InChIKey=UTRQPUXKRUOGHK-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50289324   

TargetProstaglandin G/H synthase 1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50289324(2-Isopropyl-5-(4-methanesulfonyl-phenyl)-6-phenyl-...)
Affinity DataIC50: 600nMAssay Description:Tested in vitro for the ability to inhibit Prostaglandin G/H synthase 1 in chinese hamster ovary (CHO) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetProstaglandin G/H synthase 2(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50289324(2-Isopropyl-5-(4-methanesulfonyl-phenyl)-6-phenyl-...)
Affinity DataIC50: 11nMAssay Description:In vivo ability to inhibit Prostaglandin G/H synthase 2 in human whole blood assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetProstaglandin G/H synthase 2(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50289324(2-Isopropyl-5-(4-methanesulfonyl-phenyl)-6-phenyl-...)
Affinity DataIC50: 1.10E+7nMAssay Description:Inhibition of COX2 (unknown origin) expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article