BDBM50289314 6-(4-Methanesulfonyl-phenyl)-2-methyl-5-phenyl-imidazo[2,1-b]thiazole::CHEMBL149040

SMILES Cc1cn2c(c(nc2s1)-c1ccc(cc1)S(C)(=O)=O)-c1ccccc1

InChI Key InChIKey=LHHQTSWMKWHJJH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50289314   

TargetProstaglandin G/H synthase 1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50289314(6-(4-Methanesulfonyl-phenyl)-2-methyl-5-phenyl-imi...)
Affinity DataIC50: 5.00E+4nMAssay Description:In vivo ability to inhibit cyclooxygenase-1 enzyme in human whole blood was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetProstaglandin G/H synthase 2(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50289314(6-(4-Methanesulfonyl-phenyl)-2-methyl-5-phenyl-imi...)
Affinity DataIC50: 140nMAssay Description:In vitro inhibition of the production of PGE-2 in arachidonic acid stimulated chinese hamster ovary (CHO) cells transfected with human cyclooxygenase...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article