BDBM50289311 5-(4-Methanesulfonyl-phenyl)-6-phenyl-imidazo[2,1-b]thiazole-3-carboxylic acid::CHEMBL345333

SMILES CS(=O)(=O)c1ccc(cc1)-c1c(nc2scc(C(O)=O)n12)-c1ccccc1

InChI Key InChIKey=JZHKTSLRQJSESM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50289311   

TargetProstaglandin G/H synthase 1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50289311(5-(4-Methanesulfonyl-phenyl)-6-phenyl-imidazo[2,1-...)
Affinity DataIC50: 5.00E+4nMAssay Description:In vivo ability to inhibit cyclooxygenase-1 enzyme in human whole blood was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetProstaglandin G/H synthase 2(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50289311(5-(4-Methanesulfonyl-phenyl)-6-phenyl-imidazo[2,1-...)
Affinity DataIC50: 5.00E+3nMAssay Description:In vitro inhibition of the production of PGE-2 in arachidonic acid stimulated chinese hamster ovary (CHO) cells transfected with human cyclooxygenase...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article