BDBM50289222 3-Benzo[1,3]dioxol-5-yl-5-benzyloxy-1-(4-methoxy-benzyl)-1H-indole-2-carboxylic acid::CHEMBL10092

SMILES COc1ccc(Cn2c(C(O)=O)c(-c3ccc4OCOc4c3)c3cc(OCc4ccccc4)ccc23)cc1

InChI Key InChIKey=GTEPOVNRRKKMRR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50289222   

TargetEndothelin receptor type B(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50289222(3-Benzo[1,3]dioxol-5-yl-5-benzyloxy-1-(4-methoxy-b...)
Affinity DataIC50: 4.40E+3nMAssay Description:Compound was evaluated for binding affinity against human Endothelin B receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetEndothelin-1 receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50289222(3-Benzo[1,3]dioxol-5-yl-5-benzyloxy-1-(4-methoxy-b...)
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibitory concentration to the endothelin A receptor expressed in LtK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article