BDBM50289172 CHEMBL367569::Macrocyclic Quinazolinone analogue

SMILES CCCc1nc2ccc3NCCCCCCCC(=O)NS(=O)(=O)c4ccccc4-c4ccc(Cn1c(=O)c2c3)cc4

InChI Key InChIKey=ZRPWXHWTTSCYAL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50289172   

TargetType-1 angiotensin II receptor(Rabbit)
TBA

Curated by ChEMBL
LigandPNGBDBM50289172(Macrocyclic Quinazolinone analogue | CHEMBL367569)
Affinity DataIC50: 0.300nMAssay Description:Inhibition of [125I]-Sar1-Ile8-Ang II binding to Angiotensin II receptor type 1 from rabbit aortaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetType-2 angiotensin II receptor(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50289172(Macrocyclic Quinazolinone analogue | CHEMBL367569)
Affinity DataIC50: 200nMAssay Description:Inhibition of [125I]-Sar1-Ile8-Ang II binding to rat midbrain Angiotensin II receptor type 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article