BDBM50289072 4-Hydroxy-3-(2-isopropyl-phenylsulfanyl)-6-(5-oxo-5-piperazin-1-yl-pentyl)-6-phenyl-5,6-dihydro-pyran-2-one::CHEMBL423618

SMILES CC(C)c1ccccc1SC1C(=O)CC(CCCCC(=O)N2CCNCC2)(OC1=O)c1ccccc1

InChI Key InChIKey=JXNKAJFWSWUXLL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50289072   

TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
TBA

Curated by ChEMBL
LigandPNGBDBM50289072(4-Hydroxy-3-(2-isopropyl-phenylsulfanyl)-6-(5-oxo-...)
Affinity DataIC50: 234nMpH: 4.7Assay Description:In vitro inhibitory activity against purified HIV-1 protease at a pH of 4.7 and a final enzyme concentration of 0.45-1.1 nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article