BDBM50289000 2-(2-Methoxy-phenyl)-benzo[d][1,3]oxazin-4-one::2-(2-Methoxyphenyl)-4H-3,1-benzoxazin-4-one (2)::CHEMBL349853

SMILES COc1ccccc1-c1nc2ccccc2c(=O)o1

InChI Key InChIKey=UAVIZUPEDGFRTN-UHFFFAOYSA-N

Data  1 KI  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50289000   

TargetChymotrypsinogen A(Bovine)
University of Karachi

LigandPNGBDBM50289000(2-(2-Methoxy-phenyl)-benzo[d][1,3]oxazin-4-one | C...)
Affinity DataIC50: 9.90E+3nMpH: 7.6Assay Description:The α-chymotrypsin inhibition activity was evaluated in 50 mM Tris-HCl buffer pH 7.6 with 10 mM CaCl2. α-Chymotrypsin (bovine pancreas) at ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2017
Entry Details Article
PubMed
TargetComplement C1r subcomponent(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50289000(2-(2-Methoxy-phenyl)-benzo[d][1,3]oxazin-4-one | C...)
Affinity DataIC50: 6.25E+4nMAssay Description:Inhibitory activity against C1r serine proteaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetComplement C1r subcomponent(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50289000(2-(2-Methoxy-phenyl)-benzo[d][1,3]oxazin-4-one | C...)
Affinity DataIC50: 6.25E+4nMAssay Description:Inhibitory activity against C1r serine proteaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetComplement C1r subcomponent(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50289000(2-(2-Methoxy-phenyl)-benzo[d][1,3]oxazin-4-one | C...)
Affinity DataIC50: 1.77E+4nMAssay Description:Compound was evaluated for percentage inhibitory activity against C1r serine protease in assay 1.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetChymotrypsinogen A(Bovine)
University of Karachi

LigandPNGBDBM50289000(2-(2-Methoxy-phenyl)-benzo[d][1,3]oxazin-4-one | C...)
Affinity DataKi:  1.25E+4nMAssay Description:The change in optical density per minute (OD/min) was obtained by incorporating various concentrations of compounds over a range of substrate (SPpNA)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2017
Entry Details Article
PubMed