BDBM50288818 (R)-4-[(1S,2S)-3-(3,4-Dichloro-phenyl)-2-(2-fluoro-biphenyl-4-yl)-1-methyl-propylcarbamoyl]-3-methyl-butyric acid::CHEMBL356514

SMILES C[C@@H](CC(O)=O)CC(=O)N[C@@H](C)[C@@H](Cc1ccc(Cl)c(Cl)c1)c1ccc(c(F)c1)-c1ccccc1

InChI Key InChIKey=QZWRZJBKAUEGBI-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50288818   

TargetSqualene synthase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50288818((R)-4-[(1S,2S)-3-(3,4-Dichloro-phenyl)-2-(2-fluoro...)
Affinity DataIC50: 3.90nMAssay Description:Inhibitory activity against squalene synthase (SQS) obtained from HepG2 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article