BDBM50288742 CHEMBL4164277

SMILES N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@H](Cc1cccc2ccccc12)C(=O)NCC(=O)NCCCC[C@@H](NC(=O)CNC(=O)CNC(=O)[C@H]1Cc2ccccc2CN1C(=O)[C@@H](N)Cc1ccc(O)cc1)C(O)=O

InChI Key InChIKey=QWRCJYXCNVLMHJ-UHFFFAOYSA-N

Data  2 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50288742   

TargetMu-type opioid receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50288742(CHEMBL4164277)
Affinity DataIC50: 1.00E+3nMAssay Description:Antagonist activity at human MOR expressed in CHO cell membranes assessed as inhibition of CYM51010-induced [35S]-GTPgammaS binding preincubated for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2020
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50288742(CHEMBL4164277)
Affinity DataIC50: 58nMAssay Description:Antagonist activity at human DOR expressed in CHO cell membranes assessed as inhibition of CYM51010-induced [35S]-GTPgammaS binding preincubated for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2020
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50288742(CHEMBL4164277)
Affinity DataKi:  270nMAssay Description:Displacement of [3H]-diprenorphine from human DOR expressed in CHO cell membranes after 80 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2020
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50288742(CHEMBL4164277)
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [3H]-diprenorphine from human MOR expressed in CHO cell membranes after 80 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2020
Entry Details Article
PubMed