BDBM50288587 2-(4-amino-5-chloro-2,3-dihydrobenzo[b]furan-7-ylcarboxamido)-(2S)-4-azabicyclo[2.2.2]octane::CHEMBL91147

SMILES Nc1c2CCOc2c(cc1Cl)C(=O)N[C@@H]1CN2CCC1CC2

InChI Key InChIKey=RZYIIEGPJPMBOE-UHFFFAOYSA-N

Data  2 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50288587   

Target5-hydroxytryptamine receptor 4(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50288587(2-(4-amino-5-chloro-2,3-dihydrobenzo[b]furan-7-ylc...)
Affinity DataEC50:  19nMAssay Description:In vitro relaxation of carbachol pre-contracted rat oesophageal TMM.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/27/2012
Entry Details Article

LigandPNGBDBM50288587(2-(4-amino-5-chloro-2,3-dihydrobenzo[b]furan-7-ylc...)
Affinity DataKi:  0.100nMAssay Description:Binding affinity at 5-hydroxytryptamine 3 receptor in rat entorhinal cortex by [3H]BRL-43694 displacement.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/27/2012
Entry Details Article

Target5-hydroxytryptamine receptor 4(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50288587(2-(4-amino-5-chloro-2,3-dihydrobenzo[b]furan-7-ylc...)
Affinity DataKi:  17nMAssay Description:Binding affinity at 5-hydroxytryptamine 4 receptor in rat striatum by [3H]GR-113808 displacement.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/27/2012
Entry Details Article