BDBM50288556 2-Acridin-9-yl-3-benzo[1,3]dioxol-5-yl-propionic acid methyl ester::CHEMBL100005

SMILES COC(=O)C(Cc1ccc2OCOc2c1)c1c2ccccc2nc2ccccc12

InChI Key InChIKey=KXSQTEDQWJHEDB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50288556   

TargetEndothelin-1 receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50288556(2-Acridin-9-yl-3-benzo[1,3]dioxol-5-yl-propionic a...)
Affinity DataIC50: 2.50E+4nMAssay Description:Compound was tested for its ability to inhibit Endothelin A receptor induced arachidonic acid release(AARA) in rabbit renal artery vascular smooth mu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetEndothelin-1 receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50288556(2-Acridin-9-yl-3-benzo[1,3]dioxol-5-yl-propionic a...)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of binding of [125I]ET1 to cloned human Endothelin A receptor expressed in LtK- cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article