BDBM50288541 Acridin-9-yl-benzo[1,3]dioxol-5-yl-acetic acid 4-methoxy-benzyl ester::CHEMBL101239

SMILES COc1ccc(COC(=O)C(c2ccc3OCOc3c2)c2c3ccccc3nc3ccccc23)cc1

InChI Key InChIKey=XRBYSZSXEPYWSC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50288541   

TargetEndothelin-1 receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50288541(Acridin-9-yl-benzo[1,3]dioxol-5-yl-acetic acid 4-m...)
Affinity DataIC50: 3.40E+4nMAssay Description:Inhibition of binding of [125I]ET1 to cloned human Endothelin A receptor expressed in LtK- cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetEndothelin-1 receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50288541(Acridin-9-yl-benzo[1,3]dioxol-5-yl-acetic acid 4-m...)
Affinity DataIC50: 8.20E+3nMAssay Description:Antagonistic activity against endothelin A receptor in rabbit renal artery vascular smooth muscle cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article